amodiaquine

Ligand id: 10018

Name: amodiaquine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 48.39
Molecular weight 355.15
XLogP 4.03
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Ligand families/groups Antimalarial ligands
Approved drug? Yes
IUPAC Name
4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol
International Nonproprietary Names
INN number INN
1116 amodiaquine
Synonyms
Alphaquine® | Amdaquine® | Amoquin® | Camoquin® | Flavoquine®
Comments
Amodiaquine is the non-proprietary name of the active antimalarial that is contained in a number of drugs that are approved in jurisdictions in Africa (Kenya and Tanzania), Colombia and Pakistan. It is a 4-aminoquinoline compound related to chloroquine.

Potential Target/Mechanism Of Action: As the precise mechanism of action of amodiaquine is not yet known, we do not have a molecular target for this compound.
Database Links
BindingDB Ligand 50041457
CAS Registry No. 86-42-0 (source: PubChem)
ChEMBL Ligand CHEMBL682
DrugBank Ligand DB00613
GtoPdb PubChem SID 375973208
PubChem CID 2165
RCSB PDB Ligand CQA
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