VU6012962

Ligand id: 10196

Name: VU6012962

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 86.98
Molecular weight 448.14
XLogP 3.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-(cyclopropylmethoxy)-3-methoxy-N-[2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl]benzamide
Synonyms
compound 7d [PMID: 30608678]
Comments
VU6012962 is an orally bioavailable, CNS-penetrant negative allosteric modulator of glutamate metabotropic receptor 7 (mGlu7) that is suitable as a research probe [1].
Database Links
GtoPdb PubChem SID 381118906
Search Google for chemical match using the InChIKey IQNLJJLZIVCGFI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone IQNLJJLZIVCGFI
Search UniChem for chemical match using the InChIKey IQNLJJLZIVCGFI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone IQNLJJLZIVCGFI