BL-1249

Ligand id: 10336

Name: BL-1249

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 66.49
Molecular weight 291.15
XLogP 4.94
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[2-(2H-tetrazol-5-yl)phenyl]-5,6,7,8-tetrahydronaphthalen-1-amine
Synonyms
BL1249
Comments
BL-1249 is a K2P channel activator [1]. It activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) ∼10-fold more potently than K2P4.1 (TRAAK).
Database Links
BindingDB Ligand 50197060
CAS Registry No. 18200-13-0 (source: PubChem)
ChEMBL Ligand CHEMBL1417584
GtoPdb PubChem SID 381745017
PubChem CID 16078951
Search Google for chemical match using the InChIKey YYNRZIFBTOUICE-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YYNRZIFBTOUICE
Search UniChem for chemical match using the InChIKey YYNRZIFBTOUICE-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YYNRZIFBTOUICE

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Tocris
BL 1249
Cat. No. 3797