rosiglitazone

Ligand Id: 1056
Ligand name rosiglitazone

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 96.83
Molecular weight 357.11
XLogP 2.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1999))
IUPAC Name
5-[[4-[2-(methyl-pyridin-2-ylamino)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
International Nonproprietary Names
INN number INN
7662 rosiglitazone
Synonyms
Avandia®
rosiglizole
Database Links
BindingDB Ligand 28681
CAS Registry No. 122320-73-4 (source: ChEBI)
ChEBI CHEBI:50122
ChEMBL Ligand CHEMBL121
DrugBank Ligand DB00412
Human Metabolome Database HMDB05031
NURSA Ligand li6
PharmGKB Drug PA451283
PubChem CID 77999
RCSB PDB Ligand BRL
Search Google for chemical match using the InChIKey YASAKCUCGLMORW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YASAKCUCGLMORW
Search PubMed clinical trials rosiglitazone
Search PubMed titles rosiglitazone
Search PubMed titles/abstracts rosiglitazone
Wikipedia Rosiglitazone
Comments
Marketed formulations may contain rosiglitazone maleate (PubChem CID 5281055).