Synonyms: compound 9f [PMID: 25782055] | RPX-7009 | RPX7009 | Vabomere (vaborbactam + meropenem)
vaborbactam is an approved drug (FDA (2017), EMA (2018))
Compound class:
Synthetic organic
Comment: Vaborbactam is a β-lactamase inhibitor [3]. Structurally it is based on a cyclic boronic acid pharmacophore.
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2017), EMA (2018)) |
WHO Essential Medicine | WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version. Click to view more information about the WHO Model Lists of Essential Medicines. |
IUPAC Name |
2-[(3R,6S)-2-hydroxy-3-[(2-thiophen-2-ylacetyl)amino]oxaborinan-6-yl]acetic acid |
International Nonproprietary Names | |
INN number | INN |
10182 | vaborbactam |
Synonyms |
compound 9f [PMID: 25782055] | RPX-7009 | RPX7009 | Vabomere (vaborbactam + meropenem) |
Database Links | |
Specialist databases | |
Antibiotic DB | Vaborbactam, RPX7009 + meropenem (Vabomere) | Vaborbactam, RPX7009 |
Other databases | |
DrugCentral Ligand | 5253 |
GtoPdb PubChem SID | 405560312 |
PubChem CID | 56649692 |
RCSB PDB Ligand | 4D6 |
Search Google for chemical match using the InChIKey | IOOWNWLVCOUUEX-WPRPVWTQSA-N |
Search Google for chemicals with the same backbone | IOOWNWLVCOUUEX |
Search PubMed clinical trials | vaborbactam |
Search PubMed titles | vaborbactam |
Search PubMed titles/abstracts | vaborbactam |
UniChem Compound Search for chemical match using the InChIKey | IOOWNWLVCOUUEX-WPRPVWTQSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | IOOWNWLVCOUUEX-WPRPVWTQSA-N |