glucagon-like peptide 2-(3-33)

Ligand id: 1144

Name: glucagon-like peptide 2-(3-33)

Abbreviated name: GLP-2 (3-33)

Species: Rat

Classification
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
Gcg glucagon Rat preproglucagon GLP-1, glucagon, glucagon-like peptide-1
Database Links
UniProtKB P06883 (Rn)
Comments
Rat GLP-2(3-33) is different from mouse by one residue in position 9 (Asparagine) but different by two residues from human in positions 9 (Asparagine) and 17 (Threonine).

GLP-2(3-33) is the result of N-terminal dipeptide proteolytic cleavage of GLP-2(1-33) by serine protease dipeptidyl peptidase IV. GLP-2(3-33) is able to interact with GLP-2 receptors even though it remains unclear whether GLP-2(3-33) has a biological activity in vivo or may affect the biological activity of GLP-2(1-33) [2].