(R)-cetirizine

Ligand id: 1214

Name: (R)-cetirizine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 53.01
Molecular weight 388.16
XLogP 4.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (2007))
IUPAC Name
2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid
International Nonproprietary Names
INN number INN
7700 levocetirizine
Synonyms
Vozet®
Xyzal®
Database Links
CAS Registry No. 130018-77-8
ChEMBL Ligand CHEMBL1201191
PubChem CID 1549000
RCSB PDB Ligand LCR
Search Google for chemical match using the InChIKey ZKLPARSLTMPFCP-OAQYLSRUSA-N
Search Google for chemicals with the same backbone ZKLPARSLTMPFCP
Search PubMed clinical trials levocetirizine
Search PubMed titles levocetirizine
Search PubMed titles/abstracts levocetirizine
Wikipedia Levocetirizine
Comments
Levocetirizine is an antihistamine, and is a component of the approved drug cetirizine, but this enantiomer is approved in its own right.