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Synonyms: REGN-1979 | REGN1979
Compound class:
Antibody
Comment: Odronextamab (REGN1979) is a fully human CD3ε/CD20 bispecific IgG4-based antibody that redirects CD3+ cytotoxic T cells to selectively destroy CD20+ve malignant B cells [2]. Fc-mediated effector function has been minimised by modification of the IgG4 Fc domain.
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Classification  |
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| Compound class | Antibody |
| International Nonproprietary Names |
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| INN number | INN |
| 11035 | odronextamab |
| Synonyms |
| REGN-1979 | REGN1979 |
| Database Links |
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| Specialist databases | |
| IMGT/mAb-DB | 962 |
| Other databases | |
| GtoPdb PubChem SID | 483123238 |
| Search PubMed clinical trials | odronextamab |
| Search PubMed titles | odronextamab |
| Search PubMed titles/abstracts | odronextamab |
