neurotensin

Ligand id: 1579

Name: neurotensin

Species: Human, Mouse, Rat, Bovine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: neurotensin

Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
IUPAC Name
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-4-amino-2-[[(2S)-4-carboxy-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[(2S)-4-methyl-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]amino]propanoyl]amino]butanoyl]amino]-4-oxobutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
Synonyms
NT
Comments
Note that the sequence for bovine neurotensin is the same as the human and rodent peptides.
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
NTS neurotensin Human pro-neurotensin/neuromedin neuromedin N
Nts neurotensin Mouse pro-neurotensin/neuromedin neuromedin N, NMN-125, NT/N, NTS1
Nts neurotensin Rat pro-neurotensin/neuromedin LOC299757, neuromedin N, neurotensin, neurotensin/neuromedin N, neurotensin/neuromedin N gene
NTS neurotensin Bovine pro-neurotensin/neuromedin N -
Database Links
CAS Registry No. 55508-42-4 (source: Scifinder)
ChEMBL Ligand CHEMBL407196
GtoPdb PubChem SID 135651816
PubChem CID 25077406
Search Google for chemical match using the InChIKey PCJGZPGTCUMMOT-ISULXFBGSA-N
Search Google for chemicals with the same backbone PCJGZPGTCUMMOT
Search UniChem for chemical match using the InChIKey PCJGZPGTCUMMOT-ISULXFBGSA-N
Search UniChem for chemicals with the same backbone PCJGZPGTCUMMOT
UniProtKB P01156 (Bt), P30990 (Hs), Q9D3P9 (Mm), P20068 (Rn)
Wikipedia Neurotensin