levocabastine

Ligand id: 1586

Name: levocabastine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 64.33
Molecular weight 420.22
XLogP 6.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1993))
International Nonproprietary Names
INN number INN
5393 levocabastine
Synonyms
levocobastine | Livostin®
Database Links
CAS Registry No. 79516-68-0 (source: Scifinder)
ChEMBL Ligand CHEMBL1615438
DrugBank Ligand DB01106
GtoPdb PubChem SID 135650515
PubChem CID 54385
Search Google for chemical match using the InChIKey ZCGOMHNNNFPNMX-KYTRFIICSA-N
Search Google for chemicals with the same backbone ZCGOMHNNNFPNMX
Search PubMed clinical trials levocabastine
Search PubMed titles levocabastine
Search PubMed titles/abstracts levocabastine
Search UniChem for chemical match using the InChIKey ZCGOMHNNNFPNMX-KYTRFIICSA-N
Search UniChem for chemicals with the same backbone ZCGOMHNNNFPNMX
Wikipedia Levocabastine
Comments
In addition to acting at the histamine H1 receptor, levocabastine is also a selective antagonist for the neurotensin receptor NTS2, and has been used to characterise the different receptor subtypes [5,5]. This ligand is represented on PubChem by CID 54385.