[<sup>111</sup>In]DOTA-NOC-ATE | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY

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Ligands
[¹¹¹In]DOTA-NOC-ATE

[¹¹¹In]DOTA-NOC-ATE

Ligand id: 2064

Name: [¹¹¹In]DOTA-NOC-ATE

Summary
Biological activity
References
Structure

Classification
Compound class	Peptide or derivative

Synonyms
Names	References
[¹¹¹In-DOTA]-NOC-ATE	1
[In^III-DOTA]-NOC-ATE
[InIII-DOTA]-NOC-ATE

Comments
Synthetic radiolabelled peptide. The amino acid sequence of octreotide (SMS 201,995) is modified by replacing the phenylalanine residue at position 3 and C-terminal threoninol with benzoyl-3-thienylalanine and threonine respectively. The peptide is conjugated with DOTA (1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid) and radiolabelled with indium (¹¹¹I). The structure of the non-radiolabelled version of this ligand is shown in the reference.

Comments

Synthetic radiolabelled peptide. The amino acid sequence of octreotide (SMS 201,995) is modified by replacing the phenylalanine residue at position 3 and C-terminal threoninol with benzoyl-3-thienylalanine and threonine respectively. The peptide is conjugated with DOTA (1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid) and radiolabelled with indium (¹¹¹I). The structure of the non-radiolabelled version of this ligand is shown in the reference.

[111In]DOTA-NOC-ATE

[¹¹¹In]DOTA-NOC-ATE