neurokinin A

Ligand id: 2089

Name: neurokinin A

Abbreviated name: NKA

Species: Human, Mouse, Rat

Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
IUPAC Name
(3S)-3-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
TAC1 tachykinin precursor 1 Human preprotachykinin 1 (PPT-1) neurokinin 1, neurokinin 2, neurokinin alpha, neuromedin L, neuropeptide gamma, neuropeptide K, NKNA, NPK, substance K, substance P, TAC2, tachykinin, precursor 1, tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
Tac1 tachykinin 1 Mouse preprotachykinin 1 (PPT-1) neurokinin 1, neurokinin A, NK1, NK-1, Nkna, PPTA, PPT-A, preprotachykinin A, SP, substance P
Tac1 tachykinin, precursor 1 Rat preprotachykinin 1 (PPT-1) PPT, Ppt5fl, PPTA3, protachykinin-1, RATPPTA3, TAC, tachykinin, tachykinin 1, tachykinin, precursor 1, Tachykinin (substance P neurokinin A neuropeptide K neuropeptide gamma), Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma)
Synonyms
substance K
Database Links
BindingDB Ligand 50001447
CAS Registry No. 86933-74-6 (source: Scifinder)
ChEMBL Ligand CHEMBL217406
PubChem CID 5311311
Search Google for chemical match using the InChIKey HEAUFJZALFKPBA-JPQUDPSNSA-N
Search Google for chemicals with the same backbone HEAUFJZALFKPBA
Search UniChem for chemical match using the InChIKey HEAUFJZALFKPBA-JPQUDPSNSA-N
Search UniChem for chemicals with the same backbone HEAUFJZALFKPBA
UniProtKB P20366 (Hs), P41539 (Mm), P06767 (Rn)
Wikipedia Neurokinin_A