lidocaine

Ligand id: 2623

Name: lidocaine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: lidocaine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 32.34
Molecular weight 234.17
XLogP 2.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1948))
IUPAC Name
2-diethylamino-N-(2,6-dimethylphenyl)acetamide
International Nonproprietary Names
INN number INN
4202 lidocaine
Synonyms
Xylocaine®
Database Links
BindingDB Ligand 50017662
CAS Registry No. 137-58-6
ChEBI CHEBI:6456
ChEMBL Ligand CHEMBL79
DrugBank Ligand DB00281
GtoPdb PubChem SID 135650521
PubChem CID 3676
RCSB PDB Ligand LQZ
Search Google for chemical match using the InChIKey NNJVILVZKWQKPM-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NNJVILVZKWQKPM
Search PubMed clinical trials lidocaine
Search PubMed titles lidocaine
Search PubMed titles/abstracts lidocaine
Search UniChem for chemical match using the InChIKey NNJVILVZKWQKPM-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone NNJVILVZKWQKPM
Wikipedia Lidocaine
Comments
Lidocaine was the first-in-class amino amide-type local anesthetic to be discovered.