T4

Ligand Id: 2635
Ligand name T4

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 92.78
Molecular weight 776.69
XLogP 2.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: FDA (2000))
IUPAC Name
(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
International Nonproprietary Names
INN number INN
453 levothyroxine sodium
Synonyms
Eltroxin®
L-thyroxine
levothyroxine
levothyroxine sodium
Database Links
BindingDB Ligand 50301375
CAS Registry No. 51-48-9
ChEBI CHEBI:18332
ChEMBL Ligand CHEMBL1624
DrugBank Ligand DB00451
Human Metabolome Database HMDB00248
PharmGKB Drug PA450221
PubChem CID 5819
RCSB PDB Ligand T44
Search Google for chemical match using the InChIKey XUIIKFGFIJCVMT-LBPRGKRZSA-N
Search Google for chemicals with the same backbone XUIIKFGFIJCVMT
Search PubMed clinical trials levothyroxine sodium
Search PubMed titles levothyroxine sodium
Search PubMed titles/abstracts levothyroxine sodium
Wikipedia Levothyroxine
Comments
Thyroid hormone receptor agonist