T4

Ligand Id: 2635
Ligand name T4

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 92.78
Molecular weight 776.69
XLogP 2.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: FDA (2000))
DrugBank groups approved
IUPAC Name
(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
International Nonproprietary Names
INN number INN
453 levothyroxine sodium
Synonyms
L-thyroxine
levothyroxine
T-4
T4
thyroxine
Database Links
BindingDB Ligand 50301375
CAS Registry No. 51-48-9 (source: DrugBank)
ChEBI CHEBI:18332
ChEMBL Ligand CHEMBL1624
DrugBank Ligand DB00451
Human Metabolome Database HMDB00248
PharmGKB Drug PA450221, PA151070295, PA164752444
PubChem CID 5819
RCSB PDB Ligand T44
Search Google for chemical match using the InChIKey XUIIKFGFIJCVMT-LBPRGKRZSA-N
Search Google for chemicals with the same backbone XUIIKFGFIJCVMT
Search PubMed clinical trials levothyroxine sodium
Search PubMed titles levothyroxine sodium
Search PubMed titles/abstracts levothyroxine sodium
Wikipedia Levothyroxine
Comments
Thyroid hormone receptor agonist