Ligand id: 2876
Name: eplerenone
View more information in the IUPHAR Pharmacology Education Project: eplerenone
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Molecular properties generated using the CDK |
Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2002)) |
IUPAC Name ![]() |
methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^{1,17}.0^{2,7}.0^{11,15}]octadecan]-6'-ene-9'-carboxylate |
International Nonproprietary Names ![]() |
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INN number | INN |
7596 | eplerenone |
Synonyms ![]() |
Inspra® | SC-66110 |
Comments |
Eplerenone is a potassium-sparing diuretic, which works by antagonising the effects of aldosterone. |
Database Links ![]() |
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BindingDB Ligand | 50324120 |
CAS Registry No. | 107724-20-9 |
ChEBI | CHEBI:31547 |
ChEMBL Ligand | CHEMBL1095097 |
DrugBank Ligand | DB00700 |
GtoPdb PubChem SID | 135650235 |
PubChem CID | 443872 |
RCSB PDB Ligand | YNU |
Search Google for chemical match using the InChIKey | JUKPWJGBANNWMW-VWBFHTRKSA-N |
Search Google for chemicals with the same backbone | JUKPWJGBANNWMW |
Search PubMed clinical trials | eplerenone |
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Search UniChem for chemical match using the InChIKey | JUKPWJGBANNWMW-VWBFHTRKSA-N |
Search UniChem for chemicals with the same backbone | JUKPWJGBANNWMW |
Wikipedia | Eplerenone |
Eplerenone
Cat. No. 2397 |