eplerenone
Ligand id: 2876
Name: eplerenone
View more information in the IUPHAR Pharmacology Education Project: eplerenone
Structure and Physico-chemical Properties
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Molecular properties generated using the CDK |
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Classification  |
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| Compound class | Synthetic organic |
| Approved drug? | Yes (FDA (2002)) |
| IUPAC Name |
| methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^{1,17}.0^{2,7}.0^{11,15}]octadecan]-6'-ene-9'-carboxylate |
| International Nonproprietary Names |
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| INN number | INN |
| 7596 | eplerenone |
| Synonyms |
| Inspra® | SC-66110 |
| Comments |
| Eplerenone is a potassium-sparing diuretic, which works by antagonising the effects of aldosterone. |
| Database Links |
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| BindingDB Ligand | 50324120 |
| CAS Registry No. | 107724-20-9 |
| ChEBI | CHEBI:31547 |
| ChEMBL Ligand | CHEMBL1095097 |
| DrugBank Ligand | DB00700 |
| GtoPdb PubChem SID | 135650235 |
| PubChem CID | 443872 |
| RCSB PDB Ligand | YNU |
| Search Google for chemical match using the InChIKey | JUKPWJGBANNWMW-VWBFHTRKSA-N |
| Search Google for chemicals with the same backbone | JUKPWJGBANNWMW |
| Search PubMed clinical trials | eplerenone |
| Search PubMed titles | eplerenone |
| Search PubMed titles/abstracts | eplerenone |
| Search UniChem for chemical match using the InChIKey | JUKPWJGBANNWMW-VWBFHTRKSA-N |
| Search UniChem for chemicals with the same backbone | JUKPWJGBANNWMW |
| Wikipedia | Eplerenone |
Product suppliers
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✖
Sponsored products disclaimer
Product supplier links are provided as a service to assist in identifying commercial suppliers of reagents that are mentioned on the IUPHAR/BPS Guide to PHARMACOLOGY database website, and do not imply their endorsement by NC-IUPHAR.
Links are provided in return for sponsorship, used to fund improvements to this database. The sponsorship account is managed and audited by the University of Edinburgh, a charitable body registered in Scotland, SC005336. If you are interested in sponsoring the database, please contact us.
✖
Eplerenone
Cat. No. 2397 |
