Classification
Compound class	Synthetic organic
Approved drug?	Yes (FDA (2002))

IUPAC Name

methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^{1,17}.0^{2,7}.0^{11,15}]octadecan]-6'-ene-9'-carboxylate

International Nonproprietary Names
INN number	INN
7596	eplerenone

Synonyms

Inspra® | SC-66110

Comments

Eplerenone is a potassium-sparing diuretic, which works by antagonising the effects of aldosterone.

Database Links
BindingDB Ligand	50324120
CAS Registry No.	107724-20-9
ChEBI	CHEBI:31547
ChEMBL Ligand	CHEMBL1095097
DrugBank Ligand	DB00700
GtoPdb PubChem SID	135650235
PubChem CID	443872
RCSB PDB Ligand	YNU
Search Google for chemical match using the InChIKey	JUKPWJGBANNWMW-VWBFHTRKSA-N
Search Google for chemicals with the same backbone	JUKPWJGBANNWMW
Search PubMed clinical trials	eplerenone
Search PubMed titles	eplerenone
Search PubMed titles/abstracts	eplerenone
Search UniChem for chemical match using the InChIKey	JUKPWJGBANNWMW-VWBFHTRKSA-N
Search UniChem for chemicals with the same backbone	JUKPWJGBANNWMW
Wikipedia	Eplerenone

Product suppliers

Eplerenone Cat. No. 2397