lorcaserin

Ligand id: 2941

Name: lorcaserin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 12.03
Molecular weight 195.08
XLogP 2.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2012))
IUPAC Name
(1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
International Nonproprietary Names
INN number INN
8765 lorcaserin
Synonyms
APD-356 | Belviq®
Comments
Lorcaserin is a selective, orally available and CNS active serotonin 2C receptor agonist that modulates appetite [2-3,5-6]. Cardiovascular safety in obese/overweight patients was reported by Bohula et al. (2018) [1].
Clinical formulations contain lorcaserin hydrochloride (PubChem CID 11673085).
Database Links
CAS Registry No. 616202-92-7 (source: Scifinder)
ChEMBL Ligand CHEMBL360328
DrugBank Ligand DB04871
GtoPdb PubChem SID 135650530
PubChem CID 11658860
Search Google for chemical match using the InChIKey XTTZERNUQAFMOF-QMMMGPOBSA-N
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Wikipedia Lorcaserin