ACTH

Ligand id: 3633

Name: ACTH

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Approved drug? Yes (source: FDA (1950))
International Nonproprietary Names
INN number INN
1366 corticotropin
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
POMC proopiomelanocortin Human pro-opiomelanocortin ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte stimulating hormone, beta-endorphin, beta-lipotropin, beta-melanocyte stimulating hormone, CLIP, LPH, MSH, NPP, POC
Synonyms
Acthar®
adrenocorticotropic hormone (1-39)
corticotropin
Database Links
CAS Registry No. 12279-41-3 (Hs)
ChEMBL Ligand CHEMBL1201610
DrugBank Ligand DB01285
Ensembl Gene ENSG00000115138 (Hs)
Entrez Gene 5443 (Hs)
Search PubMed clinical trials corticotropin
Search PubMed titles corticotropin
Search PubMed titles/abstracts corticotropin
UniProtKB P01189 (Hs)
Wikipedia ACTH
Comments
This is an enodgenous pepetide secreted by the pituitary gland, but is used as a drug with the approved name of corticotropin. Corticotropin is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress.