Classification
Compound class	Endogenous peptide in human, mouse or rat
Approved drug?	Yes (source: FDA (1950))

International Nonproprietary Names
INN number	INN
1366	corticotropin

Gene/Precursor

Gene symbol Gene name Species Precursor protein name Synonyms POMC proopiomelanocortin Human pro-opiomelanocortin ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte stimulating hormone, beta-endorphin, beta-lipotropin, beta-melanocyte stimulating hormone, CLIP, LPH, MSH, NPP, POC

Synonyms

Acthar®

adrenocorticotropic hormone (1-39)

corticotropin

Database Links
CAS Registry No.	12279-41-3 (Hs)
ChEMBL Ligand	CHEMBL1201610
DrugBank Ligand	DB01285
Ensembl Gene	ENSG00000115138 (Hs)
Entrez Gene	5443 (Hs)
Search PubMed clinical trials	corticotropin
Search PubMed titles	corticotropin
Search PubMed titles/abstracts	corticotropin
UniProtKB	P01189 (Hs)
Wikipedia	ACTH

Comments

This is an enodgenous pepetide secreted by the pituitary gland, but is used as a drug with the approved name of corticotropin. Corticotropin is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress.