SYM2081

Ligand id: 4317

Name: SYM2081

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 106.28
Molecular weight 159.05
XLogP -4.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2S,4R)-2-amino-4-methylpentanedioate
Synonyms
(2S,4R)-Me-Glu [2] | compound 52 [PMID: 10821708] | SYM 2081 | SYM-2081
Database Links
CAS Registry No. 31137-74-3 (source: Scifinder)
PubChem CID 21117106
Search Google for chemical match using the InChIKey KRKRAOXTGDJWNI-DMTCNVIQSA-L
Search Google for chemicals with the same backbone KRKRAOXTGDJWNI
Search UniChem for chemical match using the InChIKey KRKRAOXTGDJWNI-DMTCNVIQSA-L
Search UniChem for chemicals with the same backbone KRKRAOXTGDJWNI
Comments
SYM2081 is a potent agonist of the kainate receptors GluK1 and GluK2 (formerly GluR5 and GluR6) [1].