XCL2

Ligand id: 4370

Name: XCL2

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Synonyms
C motif cytokine 2 | lymphotactin β
Comments
XCL2 is a C subfamily chemokine, closely related to XCL1. It alternates between monomeric and dimeric states under physiological NaCl and temperature conditions. The monomeric form activates its G protein-coupled receptor XCR1, and the dimeric form is important for glycosaminoglycan (GAG) binding [1].
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
XCL2 X-C motif chemokine ligand 2 Human chemokine (C motif) ligand 2 chemokine (C motif) ligand 2, SCM-1b, SCYC2, small inducible cytokine subfamily C, member 2
Database Links
Ensembl Gene ENSG00000143185 (Hs)
GtoPdb PubChem SID 135651921
Human Protein Atlas ENSG00000143185 (Hs)
OMIM 604828 (Hs)
RefSeq Protein NP_003166 (Hs)
UniProtKB Q9UBD3 (Hs)
Wikipedia XCL2 (Hs)