thrombin

Ligand id: 4453

Name: thrombin

Species: Human

This ligand is also described as a target entry: coagulation factor II, thrombin

Classification
Compound class Endogenous peptide in human, mouse or rat
Comments
Thrombin is a serine protease that acts as an agonist at the protease-activated GPCR family. Active thrombin is a complex between thrombin light chain and thrombin heavy chain. The chains are linked by a disulphide bond between cysteine residues at position 9 of the light chain and 118 of the heavy chain.
Database Links
CAS Registry No. 9002-04-4 (source: Scifinder)
CATH/Gene3D 4.10.140.10, 4.10.740.10
DrugBank Target P00734 (Hs)
GtoPdb PubChem SID 135651891
UniProtKB P00734 (Hs)
Wikipedia Thrombin