fenfluramine

Ligand id: 4613

Name: fenfluramine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 12.03
Molecular weight 231.12
XLogP 4.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
ethyl({1-[3-(trifluoromethyl)phenyl]propan-2-yl})amine
International Nonproprietary Names
INN number INN
5818 dexfenfluramine
1596 fenfluramine
Synonyms
Adifax® | Pondimin®
Database Links
CAS Registry No. 458-24-2 (source: Scifinder)
ChEBI CHEBI:5000
ChEMBL Ligand CHEMBL87493
DrugBank Ligand DB01191
GtoPdb PubChem SID 178101333
PubChem CID 3337
Search Google for chemical match using the InChIKey DBGIVFWFUFKIQN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DBGIVFWFUFKIQN
Search PubMed clinical trials fenfluramine
Search PubMed titles fenfluramine
Search PubMed titles/abstracts fenfluramine
Search UniChem for chemical match using the InChIKey DBGIVFWFUFKIQN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone DBGIVFWFUFKIQN
Wikipedia Fenfluramine
Comments
The approved drug was called dexfenfluramine, but was withdrawn from use due to adverse cardiac events [1,3].