sildenafil

Ligand Id: 4743
Ligand name sildenafil

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 117.18
Molecular weight 475.21
XLogP 1.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1998))
IUPAC Name
5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one
International Nonproprietary Names
INN number INN
7374 sildenafil
Synonyms
Viagra®
Database Links
CAS Registry No. 139755-83-2 (source: Scifinder)
ChEBI CHEBI:9139
ChEMBL Ligand CHEMBL192
DrugBank Ligand DB00203
Human Metabolome Database HMDB05039
PubChem CID 5212
Search Google for chemical match using the InChIKey BNRNXUUZRGQAQC-UHFFFAOYSA-N
Search Google for chemicals with the same backbone BNRNXUUZRGQAQC
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Wikipedia Sildenafil
Comments
Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor.
Marketed formulations may contain ildenafil citrate (PubChem CID 62853).