furosemide

Ligand id: 4839

Name: furosemide

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: furosemide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 131.01
Molecular weight 330.01
XLogP 0.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1966))
IUPAC Name
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
International Nonproprietary Names
INN number INN
1584 furosemide
Synonyms
dihydroflumethiazide | frusemide | Lasix® | methforylthiazidine
Database Links
CAS Registry No. 54-31-9 (source: Scifinder)
ChEBI CHEBI:47426
ChEMBL Ligand CHEMBL35
DrugBank Ligand DB00695
PubChem CID 3440
RCSB PDB Ligand FUN
Search Google for chemical match using the InChIKey ZZUFCTLCJUWOSV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZZUFCTLCJUWOSV
Search PubMed clinical trials furosemide
Search PubMed titles furosemide
Search PubMed titles/abstracts furosemide
Search UniChem for chemical match using the InChIKey ZZUFCTLCJUWOSV-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone ZZUFCTLCJUWOSV
Wikipedia Furosemide
Comments
Furosemide is a loop diuretic drug.