insulin-like growth factor 1

Ligand id: 4971

Name: insulin-like growth factor 1

Abbreviated name: IGF-1

Species: Human

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: insulin-like growth factor 1

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Approved drug? Yes (FDA (2005))
International Nonproprietary Names
INN number INN
6372 mecasermin
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
IGF1 insulin like growth factor 1 Human prepro-insulin-like growth factor I IGF1A, insulin-like growth factor 1 (somatomedin C)
Synonyms
CEP-151 | mechano growth factor (MGF) | myotrophin
Database Links
CATH/Gene3D 1.10.100.10
ChEMBL Ligand CHEMBL1201716
DrugBank Ligand DB01277
Ensembl Gene ENSG00000017427 (Hs)
Human Protein Atlas ENSG00000017427 (Hs)
Search PubMed clinical trials mecasermin
Search PubMed titles mecasermin
Search PubMed titles/abstracts mecasermin
UniProtKB P05019 (Hs)
Wikipedia Mecasermin, IGF1
Comments
The recombinant form of human IGF-1 is an approved drug, mecasermin.