IL-1β

Ligand id: 4974

Name: IL-1β

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interleukins
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
IL1B interleukin 1 beta Human prepro-interleukin-1 beta IL-1B, IL1-BETA, IL1F2, interleukin 1, beta
Synonyms
catabolin | interleukin-1 beta
Database Links
DrugBank Target P01584 (Hs)
Ensembl Gene ENSG00000125538 (Hs)
Human Protein Atlas ENSG00000125538 (Hs)
UniProtKB P01584 (Hs)
Wikipedia Interleukin_1
Comments
IL-1β is an IL-1 family cytokine produced from the IL1B gene. It is produced by activated macrophages as a proprotein which is cleaved by cytosolic caspase 1 to the mature, active molecule.