lymphotoxin-α

Ligand id: 5064

Name: lymphotoxin-α

Abbreviated name: TNFSF1

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Tumor necrosis factor superfamily ligands
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
LTA lymphotoxin alpha Human prepro-lymphotoxin-alpha LT, lymphotoxin alpha (TNF superfamily, member 1), TNFB, TNFSF1
Synonyms
LTα | TNFβ
Database Links
CATH/Gene3D 2.60.120.40
Ensembl Gene ENSG00000204496 (Hs)
Human Protein Atlas ENSG00000204496 (Hs)
UniProtKB P01374 (Hs)
Wikipedia Lymphotoxin_alpha
Comments
LTA (TNFβ) is a pro-inflammarory cytokine mediating a large variety of inflammatory, immunostimulatory, and antiviral responses. LTA is required during embryonic development of lymphoid organs.