FR122047

Ligand id: 5191

Name: FR122047

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 83.14
Molecular weight 423.16
XLogP 3.35
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-{[bis(4-methoxyphenyl)-1,3-thiazol-2-yl]carbonyl}-4-methylpiperazine hydrochloride
Synonyms
FR 122047 | FR 122047 hydrochloride | FR-122047
Database Links
CAS Registry No. 130717-51-0
PubChem CID 196841
Search Google for chemical match using the InChIKey UBHKJRYGKOSQDJ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone UBHKJRYGKOSQDJ
Search UniChem for chemical match using the InChIKey UBHKJRYGKOSQDJ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone UBHKJRYGKOSQDJ
Comments
FR122047 is an orally active, selective cyclooxygenase-1 (COX-1) inhibitor with antiplatelet, analgesic and anti-inflammatory actions in vivo. Used experimentally as the hydrochloride salt (PubChem CID 196840).