guanfacine

Ligand id: 522

Name: guanfacine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 81.47
Molecular weight 245.01
XLogP 1.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1986))
IUPAC Name
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide
International Nonproprietary Names
INN number INN
3999 guanfacine
Synonyms
Estulic® | Tenex®
Database Links
BindingDB Ligand 81984
CAS Registry No. 29110-47-2
ChEMBL Ligand CHEMBL862
DrugBank Ligand DB01018
GtoPdb PubChem SID 135650327
PubChem CID 3519
Search Google for chemical match using the InChIKey INJOMKTZOLKMBF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone INJOMKTZOLKMBF
Search PubMed clinical trials guanfacine
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Search UniChem for chemical match using the InChIKey INJOMKTZOLKMBF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone INJOMKTZOLKMBF
Wikipedia Guanfacine
Comments
Guanfacine is a centrally acting sympatholytic drug acting via activation of α2-adrenoceptors.