alvocidib

Ligand id: 5680

Name: alvocidib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 90.23
Molecular weight 401.1
XLogP 1.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one
International Nonproprietary Names
INN number INN
8125 alvocidib
Synonyms
flavopiridol
HL 275
HMR 1275
L 86-8275
L 868275
MDL-107826A
NSC-649890
Database Links
CAS Registry No. 146426-40-6
ChEMBL Ligand CHEMBL428690
DrugBank Ligand DB03496
PubChem CID 5287969
Search Google for chemical match using the InChIKey BIIVYFLTOXDAOV-YVEFUNNKSA-N
Search Google for chemicals with the same backbone BIIVYFLTOXDAOV
Search PubMed clinical trials alvocidib
Search PubMed titles alvocidib
Search PubMed titles/abstracts alvocidib
Wikipedia Alvocidib
Comments
Alvocidib is a selective inhibitor of cyclin-dependent kinase (CDK) 2 and CDK4 [2].