KW-2449

Ligand id: 5691

Name: KW-2449

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 61.02
Molecular weight 332.16
XLogP 4.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-[(E)-2-{4-[(piperazin-1-yl)carbonyl]phenyl}ethenyl]-2H-indazole
Synonyms
KW 2449
Database Links
CAS Registry No. 1000669-72-6
ChEMBL Ligand CHEMBL1908397
PubChem CID 11427553
Search Google for chemical match using the InChIKey YYLKKYCXAOBSRM-JXMROGBWSA-N
Search Google for chemicals with the same backbone YYLKKYCXAOBSRM
Search UniChem for chemical match using the InChIKey YYLKKYCXAOBSRM-JXMROGBWSA-N
Search UniChem for chemicals with the same backbone YYLKKYCXAOBSRM
Comments
KW-2449 is a multi-targeted kinase inhibitor [2] that was investigated as a treatment for leukemias with FLT3 mutations or T315I-mutated BCR/ABL translocation.