PHA-665752

Ligand id: 5700

Name: PHA-665752

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 110.96
Molecular weight 640.17
XLogP 4.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(3Z)-5-{[(2,6-dichlorophenyl)methane]sulfonyl}-3-[(3,5-dimethyl-4-{[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl}-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one
Synonyms
PHA 665752 | TCMDC-125885
Database Links
CAS Registry No. 477575-56-7
ChEMBL Ligand CHEMBL450786
PubChem CID 10461815
Search Google for chemical match using the InChIKey OYONTEXKYJZFHA-SSHUPFPWSA-N
Search Google for chemicals with the same backbone OYONTEXKYJZFHA
Search UniChem for chemical match using the InChIKey OYONTEXKYJZFHA-SSHUPFPWSA-N
Search UniChem for chemicals with the same backbone OYONTEXKYJZFHA
Comments
PHA-665752 is a potent, selective and ATP-competitive c-MET (HGFR) inhibitor [1].