PLX-4720

Ligand id: 5703

Name: PLX-4720

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 100.3
Molecular weight 413.04
XLogP 3.07
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[3-({5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide
Synonyms
PLX 4720
Database Links
CAS Registry No. 918505-84-7
ChEMBL Ligand CHEMBL1230020
PubChem CID 24180719
RCSB PDB Ligand 324
Search Google for chemical match using the InChIKey YZDJQTHVDDOVHR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YZDJQTHVDDOVHR
Search UniChem for chemical match using the InChIKey YZDJQTHVDDOVHR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YZDJQTHVDDOVHR
SynPHARM 81219 (in complex with B-Raf proto-oncogene, serine/threonine kinase)
81218 (in complex with B-Raf proto-oncogene, serine/threonine kinase)
Comments
PLX-4720 is a selective inhibitor of BRAF.