SU-14813

Ligand id: 5712

Name: SU-14813

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 7
Topological polar surface area 103.26
Molecular weight 442.2
XLogP -0.44
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-N-[(2S)-2-hydroxy-3-(morpholin-4-yl)propyl]-2,4-dimethyl-3H-pyrrole-3-carboxamide
Synonyms
SU014813 | SU14813
Database Links
CAS Registry No. 627908-92-3
PubChem CID 73755145
Search Google for chemical match using the InChIKey XWPFYHDOZULRTD-ROUJOJKSSA-N
Search Google for chemicals with the same backbone XWPFYHDOZULRTD
Search UniChem for chemical match using the InChIKey XWPFYHDOZULRTD-ROUJOJKSSA-N
Search UniChem for chemicals with the same backbone XWPFYHDOZULRTD
Comments
SU-14813 is an oral, multitargeted receptor tyrosine kinase inhibitor targeting VEGFRs, PDGFRs, KIT, and FLT3 [2-3].