IL-17C

Ligand id: 5875

Name: IL-17C

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interleukins
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
IL17C interleukin 17C Human prepro-interleukin-17C CX2, IL-17C, IL-21, MGC126884, MGC138401
Synonyms
cytokine CX2 | interleukin-17C
Database Links
CATH/Gene3D 2.10.90.10
Ensembl Gene ENSG00000124391 (Hs)
Human Protein Atlas ENSG00000124391 (Hs)
UniProtKB Q9P0M4 (Hs)
Comments
IL-17C is an IL-17 homolog, secreted by epithelial cells in response to bacterial challenge and inflammatory stimuli and that acts in an autocrine manner to control the innate epithelial immune responses necessary for regulating intestinal inflammation and barrier function [1-2].