AGL 2043

Ligand id: 5918

Name: AGL 2043

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 71.84
Molecular weight 280.08
XLogP 3.15
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1,2-dimethyl-6-(thiophen-2-yl)-1H-imidazo[4,5-g]quinoxaline
Synonyms
AGL-2043
AGL2043
HMS3229A05
Database Links
CAS Registry No. 226717-28-8
ChEMBL Ligand CHEMBL2218927
PubChem CID 9817165
Search Google for chemical match using the InChIKey ZGDACLBJJXLKJY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZGDACLBJJXLKJY
Comments
This is compound 13 in [3].
AGL 2043 is a potent, reversible, ATP-competitive inhibitor of type III receptor tyrosine kinases (PDGFR, CSFR, Kit, FLT3 receptor family).