KU-55933

Ligand id: 5928

Name: KU-55933

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 89.37
Molecular weight 395.06
XLogP 3.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-(morpholin-4-yl)-6-(thianthren-1-yl)-4H-pyran-4-one
Synonyms
ATM kinase inhibitor | KU55933
Database Links
CAS Registry No. 587871-26-9
ChEMBL Ligand CHEMBL222102
PubChem CID 5278396
Search Google for chemical match using the InChIKey XRKYMMUGXMWDAO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XRKYMMUGXMWDAO
Search UniChem for chemical match using the InChIKey XRKYMMUGXMWDAO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XRKYMMUGXMWDAO
Comments
KU-55933 is a potent and selective inhibitor of the ataxia-telangiectasia mutated (ATM) kinase [3], used to investigate the DNA damage repair response, particularly in relation to exploiting this pathway to discover novel cancer therapeutics.