IC261

Ligand id: 5985

Name: IC261

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 56.79
Molecular weight 311.12
XLogP 3.14
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-[(2,4,6-trimethoxyphenyl)methylidene]-2,3-dihydro-1H-indol-2-one
Synonyms
IC 261 | IC-261
Database Links
CAS Registry No. 186611-52-9
ChEMBL Ligand CHEMBL576349
PubChem CID 3674
Search Google for chemical match using the InChIKey JBJYTZXCZDNOJW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JBJYTZXCZDNOJW
Search UniChem for chemical match using the InChIKey JBJYTZXCZDNOJW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone JBJYTZXCZDNOJW
Comments
IC261 inhibits the activity of casein kinase 1 in an ATP-competitive manner, and is selective for the 1δ and 1ε isoforms of the enzyme.