LY 294002

Ligand id: 6004

Name: LY 294002

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 38.77
Molecular weight 307.12
XLogP 4.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one
Synonyms
LY-294002 | LY294002 | SF 1101
Database Links
CAS Registry No. 154447-36-6
ChEBI CHEBI:65329
ChEMBL Ligand CHEMBL98350
DrugBank Ligand DB02656
PubChem CID 3973
RCSB PDB Ligand LY2
Search Google for chemical match using the InChIKey CZQHHVNHHHRRDU-UHFFFAOYSA-N
Search Google for chemicals with the same backbone CZQHHVNHHHRRDU
Search UniChem for chemical match using the InChIKey CZQHHVNHHHRRDU-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone CZQHHVNHHHRRDU
SynPHARM 82041 (in complex with bromodomain containing 4)
Wikipedia LY294002
Comments
LY 294002 is a selective phosphatidylinositol 3-kinase (PI3K) inhibitor [6], with preference for PI3Kα/δ/β. LY 294002 has also been reported to interact with the unrelated BET bromodomain proteins BRD2, BRD3, and BRD4 [4].