Src kinase inhibitor I

Ligand id: 6042

Name: Src kinase inhibitor I

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 65.5
Molecular weight 373.14
XLogP 5.29
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
6,7-dimethoxy-N-(4-phenoxyphenyl)quinazolin-4-amine
Database Links
CAS Registry No. 179248-59-0
ChEMBL Ligand CHEMBL97771
PubChem CID 1474853
Search Google for chemical match using the InChIKey DMWVGXGXHPOEPT-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DMWVGXGXHPOEPT
Search UniChem for chemical match using the InChIKey DMWVGXGXHPOEPT-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone DMWVGXGXHPOEPT
Comments
This compound is used as a Src inhibitor, but it also has potent inhibitory action against the serine/threonine kinase RIPK2 ( receptor-interacting serine-threonine kinase 2) [2].