TGF-beta RI inhibitor III

Ligand id: 6049

Name: TGF-beta RI inhibitor III

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 60.03
Molecular weight 335.16
XLogP 4.7
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
2-[4-(2H-1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine
Synonyms
SB-505124 | SB505124
Database Links
CAS Registry No. 694433-59-5
ChEMBL Ligand CHEMBL226838
PubChem CID 9858940
Search Google for chemical match using the InChIKey WGZOTBUYUFBEPZ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone WGZOTBUYUFBEPZ
Search UniChem for chemical match using the InChIKey WGZOTBUYUFBEPZ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone WGZOTBUYUFBEPZ
Comments
This is compound 1 (SB-505124) in [3]. It is a selective inhibitor of TGF-βRI, ALK4 and ALK7.