Tpl2 kinase inhibitor

Ligand id: 6051

Name: Tpl2 kinase inhibitor

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 86.52
Molecular weight 404.1
XLogP 3.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[(3-chloro-4-fluorophenyl)amino]-6-[(pyridin-3-ylmethyl)amino]-1,7-naphthyridine-3-carbonitrile
Database Links
CAS Registry No. 871307-18-5
ChEMBL Ligand CHEMBL200381
PubChem CID 9549300
Search Google for chemical match using the InChIKey NMEUKWOOQOHUNA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NMEUKWOOQOHUNA
Search UniChem for chemical match using the InChIKey NMEUKWOOQOHUNA-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone NMEUKWOOQOHUNA
Comments
Tpl2 is a synonym of the human MAP3K8 (mitogen-activated protein kinase kinase kinase 8) gene.