VEGF receptor tyrosine kinase inhibitor II

Ligand id: 6056

Name: VEGF receptor tyrosine kinase inhibitor II

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 54.02
Molecular weight 337.1
XLogP 5.13
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide
Synonyms
AG-E-85378
Comments
This is compound 10 in [2]. The article does not clearly indicate the speciesused to derive the VEGFR2 protein used in the kinase assays. We map this data to the human protein.
Database Links
CAS Registry No. 269390-69-4
ChEMBL Ligand CHEMBL101683
DrugBank Ligand DB07288
GtoPdb PubChem SID 178102677
PubChem CID 9797919
RCSB PDB Ligand 8ST
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