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Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|International Nonproprietary Names|
|CAS Registry No.||848141-11-7 (source: Scifinder)|
|Search Google for chemical match using the InChIKey||QNQZWEGMKJBHEM-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||QNQZWEGMKJBHEM|
|Search PubMed clinical trials||alvelestat|
|Search PubMed titles||alvelestat|
|Search PubMed titles/abstracts||alvelestat|
|AZD9668 is a potent, selective and reversible inhibitor of human neutrophil elastase. It was developed as having the potential to be effective for neutrophil-driven inflammatory lung diseases, such as bronchiectasis and COPD . Since the phase II studies did not show clear efficacy for COPD this compound is now listed in the AstraZeneca Open Innovation Clinical Compound Bank for repurposing proposals.
There is ambiguity on PubChem in the assigned nomenclature and stuctures for this compound, as CID 71587812 has been incorrectly assigned alvelestat as a synonym.