WX-UK1

Ligand id: 6498

Name: WX-UK1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 3
Rotatable bonds 14
Topological polar surface area 154.27
Molecular weight 613.33
XLogP 6.99
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Prodrug upamostat
IUPAC Name
ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-[[2,4,6-tri(propan-2-yl)phenyl]sulfonylamino]propanoyl]piperazine-1-carboxylate
Synonyms
compound 2r-L [1] | UKI-1
Database Links
ChEMBL Ligand CHEMBL107955
PubChem CID 9895193
Search Google for chemical match using the InChIKey ISJSHQTWOHGCMM-NDEPHWFRSA-N
Search Google for chemicals with the same backbone ISJSHQTWOHGCMM
Search UniChem for chemical match using the InChIKey ISJSHQTWOHGCMM-NDEPHWFRSA-N
Search UniChem for chemicals with the same backbone ISJSHQTWOHGCMM
Comments
Drug from the prodrug upamostat. This compound has urokinase-type plasminogen activator inhbitory effect, but also inhibits other trypsin-like enzymes [1].