Classification
Compound class	Peptide or derivative

IUPAC Name

2-[(2S,5R,8S,11S)-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-5-(phenylmethyl)-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid

International Nonproprietary Names
INN number	INN
7823	cilengitide

Synonyms

EMD-12192

EMD-121974

Database Links
CAS Registry No.	188968-51-6
ChEMBL Ligand	CHEMBL429876
PubChem CID	176873
Search Google for chemical match using the InChIKey	AMLYAMJWYAIXIA-VWNVYAMZSA-N
Search Google for chemicals with the same backbone	AMLYAMJWYAIXIA
Search PubMed clinical trials	cilengitide
Search PubMed titles	cilengitide
Search PubMed titles/abstracts	cilengitide
Wikipedia	Cilengitide

Comments

Cilengitide is a pentapeptide, first-in-class integrin inhibitor. It inhibits integrin αv-induced angiogenesis. It was investigated for anti-tumour activity. Glioblastoma was one of the cancers investigated [5], based on encouraging preclinical studies in animals [3-4,6].