icatibant

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Ligands
icatibant

Ligand id: 667

Name: icatibant

Summary
Biological activity
Clinical data
References
Structure
Immunopharmacology

Classification
Compound class	Peptide or derivative
Approved drug?	Yes (source: EMA (2008), FDA (2011))

International Nonproprietary Names
INN number	INN
6922	icatibant

Synonyms
D-Arg-[Hyp³,Thi⁵,D-Tic⁷,Oic⁸]BK
Firazyr®
HOE 140
HOE140

Synonyms

D-Arg-[Hyp³,Thi⁵,D-Tic⁷,Oic⁸]BK

Firazyr®

HOE 140

HOE140

Database Links
BindingDB Ligand	50142947
CAS Registry No.	130308-48-4 (source: Scifinder)
ChEMBL Ligand	CHEMBL2028850
DrugBank Ligand	DB06196
PharmGKB Drug	PA164749185
PubChem CID	71364
Search PubMed clinical trials	icatibant
Search PubMed titles	icatibant
Search PubMed titles/abstracts	icatibant
Wikipedia	Icatibant

Comments
Synthetic analogue of bradykinin. There is some ambiguity in the literature and on online resources as to the exact chemical structure and stereochemistry of icatibant. Therefore, we have chosen not to include a chemical structure here. Users should note that there may not be agreement in the structures represented in the external links provided above.

Comments

Synthetic analogue of bradykinin. There is some ambiguity in the literature and on online resources as to the exact chemical structure and stereochemistry of icatibant. Therefore, we have chosen not to include a chemical structure here. Users should note that there may not be agreement in the structures represented in the external links provided above.