galantamine

Ligand id: 6693

Name: galantamine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 41.93
Molecular weight 287.15
XLogP 1.06
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2001))
IUPAC Name
(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
International Nonproprietary Names
INN number INN
1392 galantamine
Synonyms
galanthamine | Razadyne®
Database Links
CAS Registry No. 357-70-0 (source: PubChem)
ChEBI CHEBI:42944
ChEMBL Ligand CHEMBL659
DrugBank Ligand DB00674
PubChem CID 9651
RCSB PDB Ligand GNT
Search Google for chemical match using the InChIKey ASUTZQLVASHGKV-JDFRZJQESA-N
Search Google for chemicals with the same backbone ASUTZQLVASHGKV
Search PubMed clinical trials galantamine
Search PubMed titles galantamine
Search PubMed titles/abstracts galantamine
Search UniChem for chemical match using the InChIKey ASUTZQLVASHGKV-JDFRZJQESA-N
Search UniChem for chemicals with the same backbone ASUTZQLVASHGKV
SynPHARM 78675 (in complex with acetylcholinesterase (Cartwright blood group))
Wikipedia Galantamine
Comments
Many alternative stereo forms exist for the structure. The marketed formulation contains galantamine hydrobromide (PubChem CID 121587).