brentuximab vedotin

Ligand id: 6772

Name: brentuximab vedotin

Classification
Compound class Antibody
Approved drug? Yes (source: FDA (2011), EMA (2012))
International Nonproprietary Names
INN number INN
9144 brentuximab vedotin
Synonyms
Adcetris®
anti-CD30 ADC SGN-35
SGN 35
Database Links
Specialist databases
IMGT/mAb-DB 324
Other databases
PubChem SID 178103378
Search PubMed clinical trials brentuximab vedotin
Search PubMed titles brentuximab vedotin
Search PubMed titles/abstracts brentuximab vedotin
Wikipedia Brentuximab_vedotin
Comments
Antibody-drug conjugate (ADC) that combines an anti-CD30 antibody and the drug monomethyl auristatin E (MMAE). The PubChem ID for the MMAE component compound is CID 11542188. The invention of this ADC is claimed in patent US7090843 [2] and the original article describing the parent antibody (C10 or AC10) is [1].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.