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Ligand id: 6886
View more information in the IUPHAR Pharmacology Education Project: denosumab
|Approved drug?||Yes (FDA and EMA (2010))|
|International Nonproprietary Names|
|AMG-162 | M05BX04 | Prolia® | Xgeva®|
|Denosumab suppresses the activity of RANK ligand (RANKL), which normally promotes bone removal and resorption, but which becomes over active in many bone loss diseases.
Denosumab is produced from CHO cells stably expressing recombinant antibody component proteins .
|GtoPdb PubChem SID||178103468|
|Search PubMed clinical trials||denosumab|
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