forasartan

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Ligands
forasartan

Ligand id: 6896

Name: forasartan

Structure and Physico-chemical Properties

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	8
Hydrogen bond donors	1
Rotatable bonds	10
Topological polar surface area	98.06
Molecular weight	416.24
XLogP	7.18
No. Lipinski's rules broken	1

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic
Approved drug?	Yes

IUPAC Name
5-[(3,5-dibutyl-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-tetrazol-5-yl)phenyl]pyridine

IUPAC Name

5-[(3,5-dibutyl-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-tetrazol-5-yl)phenyl]pyridine

International Nonproprietary Names
INN number	INN
7415	forasartan

Synonyms
SC-52458

Synonyms

SC-52458

Database Links
CAS Registry No.	145216-43-9 (source: Scifinder)
ChEMBL Ligand	CHEMBL315021
DrugBank Ligand	DB01342
PubChem CID	132706
Search Google for chemical match using the InChIKey	YONOBYIBNBCDSJ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	YONOBYIBNBCDSJ
Search PubMed clinical trials	forasartan
Search PubMed titles	forasartan
Search PubMed titles/abstracts	forasartan
Wikipedia	Forasartan

Comments
Forasartan is a nonpeptide, competitive and reversible angiotensin II receptor antagonist, selective for the AT₁ receptor. Forasartan is not a popular drug of choice for hypertension as it is less effective than losartan, due to its relatively short duration of action.

Comments

Forasartan is a nonpeptide, competitive and reversible angiotensin II receptor antagonist, selective for the AT₁ receptor. Forasartan is not a popular drug of choice for hypertension as it is less effective than losartan, due to its relatively short duration of action.